TNKS and neoplasm: Wnt–β-catenin signaling is blocked by various TNKS inhibitors such as tankyrase inhibitor 49 (TNKSi49) [236], XAV939 [226], JW74 [260], AZ1366 [261], IWR-1 [234,262], NVP-TNKS656 [232], WIKI4 [237], G007-LK [233], and JW55 [231] in different tumor models.