Conversely, robust STAT3 signaling activity in M2-TAMs and N2-TANs correlates with the production of factors able to drive cancer cell EMT (OSM, IL-6, TGF-β) and angiogenesis (VEGF, TGF-β, PDGF, and FGF) [205,206,207,208]. Here, TGFB1 is linked to cancer.