At the molecular level, melanoma can be classified into four main types: v-Raf murine sarcoma viral oncogene homolog B (BRAF)-mutant, neuroblastoma RAS viral oncogene homology (NRAS)-mutant, neurofibromatosis type 1 (NF1)-mutant, and triple-negative or wild-type melanoma [1]. This evidence concerns the gene NF1 and melanoma.