To test this, we examined whether expression of NR1H3/LXRA or NR1H2/LXRB correlated with expression of canonical LXR target genes (ABCA1 and APOE) in 81 ER-negative or 234 ER-positive primary breast tumours (obtained from TCGA dataset [24]). This evidence concerns the gene ABCA1 and breast neoplasm.