HSP90B1 and colorectal carcinoma: To determine the effect of GRP94 IgG on cetuximab-resistant CRC cell growth, we used flow cytometry to determine the binding extent of GRP94 IgG or cetuximab on five CRC cell lines cetuximab-resistant HCT116, HT-29, LoVo, and HCT-8 cells and cetuximab-sensitive Caco-2 cells.