STAT3 and cancer: To confirm that the resulting decrease in the expression levels of p53, phospho-p53 and c-Myc was facilitated by the nanopolymer’s intracellular specific inhibitory actions FR, we treated PANC-1 and MDA-MB-231 cancer cells with anti-FR antibody and assessed the effects on cell viability and expression levels of p53, phospho-p53, STAT-3 and c-Myc.