At univariate analysis of patients with chronic rhinosinusitis using the following comparison groups: allergic vs. non-allergic, asthmatic vs. non-asthmatic, non-asthmatic allergic vs. non-asthmatic non-allergic, non-allergic asthmatic vs. non-allergic-non-asthmatic, the expression of ARG2 was significantly higher in patients with non-allergic CRS (FR −1.71 ± 0.14 vs. 1.37 ± 0.28, p = 0.003) (Figure 7) and non-asthmatic non-allergic patients (FR 1.03 ± 0.34 vs. 1.38 ± 0.34, p = 0.020, Figure 8). The gene discussed is ARG2; the disease is congenital rubella syndrome.