In contrast, PEP-1-PEBP1 significantly ameliorated increases of MDA, AOPP, and 8-iso-PGF2α levels in the spinal cord following ischemia, suggesting that administering PEP-1-PEBP1 reduces ischemia-induced lipid peroxidation and protein oxidation in the spinal cord. Here, PEBP1 is linked to ischemia.