Conversely, Droeser et al. [37] demonstrated that high PD-L1 expression in MMR-proficient CRC was correlated with early tumor stage, absence of lymph node metastases, lower histological grade, absence of vascular invasion, high numbers of TILs, especially CD8+ T cells, and an improved overall survival rate. The gene discussed is CD8A; the disease is colorectal carcinoma.