When analysing mutations annotated in The Catalogue of Somatic Mutations In Cancer (COSMIC) [171], one of the largest curated databases of somatic mutations, which includes additional endometrial cancer datasets [172], ACVR1 mutations are found in 2.69% (25 mutated samples out of 931 samples tested) of endometrial cancers. The gene discussed is ACVR1; the disease is endometrial cancer.