MYC and diffuse large B-cell lymphoma: Thus, although further studies are required to investigate the role of miR-17-92 in DLBCL, a plausible type 2 FFL may involve the proapoptotic PTEN tumour suppressor gene, which is a validated miR-19a target [114,154] and a direct MYC target, suggesting that MYC-induced miRNAs may coordinate the balance of cell proliferation and cell death in these lymphomas (Figure 4A T1a).