MYC and lymphoma: Since MYC was highly overexpressed in the mouse lymphomas, the downregulated miRNAs included miR-150, miR-22, miR-26a-1, and miR-26b, and the miRNA clusters miR-100–125b-1, miR-99a-125b-2, and miR-29b-2–29c, which are known MYC targets.