The most common subtypes are LGMD1A (myotilinopathy), LGMD1B (laminopathy), LGMD1C (caveolinopathy), LGMD1E and LGMD2R (desminopathies), LGMD2A (calpainopathy), LGMD2B (dysferlinopathy), LGMD2C, 2D, 2E, and 2F (the sarcoglycanopathies), LGMD2G (telethoninopathy), LGMD2I, 2K, 2M, 2N, 2O, 2P, 2T, and 2U (the dystroglycanopathies), LGMD2J (titinopathy), and LGMD2L. The gene discussed is DES; the disease is autosomal recessive limb-girdle muscular dystrophy type 2A.