TLR2 and colitis: In line with this hypothesis, dietary supplementation with probiotics Lactobacillus rhamnosus and Bifidobacterium breve led to differential effects in murine colitis models, showing preventive effects when administered prior to the induction of colitis [36], while worsening bloody diarrhoea and inducing expression of TLR2, TLR6, and pro-inflammatory markers in the case in which they are evaluated in the relapse stages of the disease [37].