Table 2 shows the genotype and allele distributions for IL-17 gene polymorphisms in the CRC patients and controls. The observed genotype frequencies for the two polymorphisms (rs2275913 and rs763780) in the controls did not departure from HWE. For rs2275913 polymorphism, A allele was related to increased risk for CRC (AA vs GG: OR, 1.31; 95% CI, 1.06–1.64; P = 0.014); the AA genotype (not GA genotype) had a significantly elevated risk for CRC compared to GG genotype (AA vs GG: OR, 1.72; 95% CI, 1.02–2.88; P = 0.041). Here, IL17A is linked to colorectal carcinoma.