IFI16 and infection: Using the same ChIP promoter primers, we found that 48 hr post-infection (p.i.)with KSHV in IFI16 depleted cells, recruitment of H3K9me3 on lytic pK8, pvIRF2 and pORF63 decreased at least by 0.5-fold (black arrows) while H3K4me3 and H3K27me3 did not change significantly.