The most frequent mutations in Japanese patients with FMF included E148Q (40.2%), M694I (21.0%), L110P (18.8%), P369S (5.4%), and R408Q (5.4%).12 In our study, the most common MEFV gene mutations were E148Q (52.9%), R202Q (11.8%), P369S (11.8%), R408Q (11.8%), E84K (5.9%), G304R (5.9%), and L110P (5.9%). Here, MEFV is linked to familial Mediterranean fever.