MNX1 and acute myeloid leukemia: The MNX1 (a.k.a. HLXB9) gene on the long arm of chromosome 7 (7q36) encodes a homeobox transcription factor that is essential for pancreatic organogenesis, and moto-neuron differentiation, and is involved in a t(7;12)(q36;p13) translocation that is a hallmark of infant AML with poor outcome (8, 40).