TIAL1 and infection: Importantly, Garaigorta et al. reported that G3BP-1, TIA-1, and TIAR are required for viral RNA and protein synthesis early during infection, while G3BP-1, DDX3, and TIA-1 play a role in viral particle assembly (Garaigorta et al., 2012; Pène et al., 2015; Valiente-Echeverría et al., 2015).