The results indicated that high expression of FTO (HR = 1.15, 95% CI = 1.02–1.29), HNRNPC (HR = 1.09, 95% CI = 1.02–1.18), YTHDC2 (HR = 1.22, 95% CI = 1.07–1.42), and WTAP (HR = 1.18, 95% CI = 1.02–1.33) have a worse survival in patients with gastric cancer. The gene discussed is YTHDC2; the disease is gastric cancer.