Previous studies mainly focused on understanding the alteration in gene expression in NSCLC tumors (7), and identified overexpressed genes including CDC20 (8), CCNB1 (9), ASPM (10), and KIF4A (11), which contributes to the proliferation of tumor cells and also associated with poor prognosis. The gene discussed is CCNB1; the disease is non-small cell lung carcinoma.