Another study found 16 hub genes (TEK, ANGPT1, MMP9, VWF, CDH5, EDN1, ESAM, CCNE1, CDC45, PRC1, CCNB2, AURKA, MELK, CDC20, TOP2A, and PTTG1) in NSCLC (95). The gene discussed is VWF; the disease is non-small cell lung carcinoma.