TGFB3 and cancer: While most of the repositioning events in intermediate/high Gleason score cancers were to a more internal position, in one cancer the only repositioning event resulted in a more peripheral location of TGFB3 and in another cancer tissue, there was both a more peripheral and more internal repositioning events, with SP100 more peripherally position and TGFB3 more internally located (Table 1, Supplementary Table 7).