AKT1 and cancer: KEGG pathway enrichment analysis of up-regulated DEGs (Figure 4B) showed that in lowland chickens “PI3K-Akt signaling,” “pathways in cancer,” “Jak-STAT signaling,” and “Toll-like receptor signaling pathway” were enriched in the cardiac tissue, and “MAPK signaling pathway,” “antigen processing and presentation,” and “cell adhesion molecules” were enriched in the skeletal muscle.