CPEB4 and autism: These findings are consistent with previous postmortem brain studies of autism that report a dysregulation of microexons (Irimia et al., 2014), aberrant alternative splicing of activity-dependent neuron-specific exons (Parikshak et al., 2016), and altered proportion of CPEB4 isoforms resulting from decreased inclusion of a neuron specific microexon (Parras et al., 2018).