ELF1 and ischemic stroke: By investigating the function of these co-targeted genes (marked by red boxes), we infer the mechanism of the interaction between miRNAs and mRNA in ischemic stroke: a) The mmu-miR-3085-3p and mmu-miR-3085-3p co-regulated Elf1 genes to promote early recovery of ischemic stroke in immune regulation and angiogenesis.