This network demonstrates that 61 exosomal molecules (Table 4) may affect tumor progression through pathways controlled by key components including MET, Ras, RAF1, Mek, ERK1/2, MITF, BCL2, PI3K, Akt, mTOR, PD-1, KIT, JAK STAT3, or ETS1. The gene discussed is PIK3CA; the disease is neoplasm.