CSF2 and chronic granulomatous disease: No statistically significant differences between healthy control and CGD macrophages were observed in this experimental series (Figure S6) and both, healthy control and CGD M1 macrophages could be re-primed to anti-inflammatory M2a phenotype by a shift to M2a stimulus for 72 h (M1M2a), judged by GM-CSF level (Figure 3C).