TRPV2 and neoplasm: These channels such as TRPV1, TRPV2, as well as other numerous members of TRP channel family play a critical role in tumorigenesis, tumor vascularization, and the ability of tumor cells to proliferate and migrate (Prevarskaya et al., 2007; Santoni and Farfariello, 2011; Fiorio Pla and Gkika, 2013; Chen et al., 2014).