CD4 and neoplasm: Heat stressed EVs (HS-EVs).HS-EVs chemoattracted CD11+ DCs and CD4+/CD8+ T cells in vitro and in vivo.In vivo3LL Lewis lung carcinoma modelIT injection of HS-EVs induced more efficient specific antitumour response in comparison with EVs - ↓ tumour growth, ↑ survival.