Mitochondrial calcium uptake 1 (MICU1) is a mitochondrial inner membrane protein that regulates the transport of Ca2+ through the mitochondrial calcium uniporter (MCU) and plays a role in maintaining the homeostasis of Ca2+ in mitochondria, thus playing a vital role in influencing cardiovascular disease (Mallilankaraman et al., 2012). This evidence concerns the gene MCU and cardiovascular disorder.