For instance, netrin-G1 is associated with Rett syndrome, ASD, schizophrenia and bipolar disorder (Borg et al., 2005; Archer et al., 2006; Nectoux et al., 2007; Eastwood and Harrison, 2008; Ohtsuki et al., 2008; O’Roak et al., 2012). Here, NTNG1 is linked to atypical Rett syndrome.