Previously, studies related to LHb have mostly been focused on depression, fear learning and substance use (Płażnik et al., 1980; Borelli et al., 2005; Sartorius et al., 2010; Maroteaux and Mameli, 2012; Li et al., 2013; Batalla et al., 2017). The gene discussed is LHB; the disease is depressive symptom measurement.