N-Acetylglucosamine levels seem to be increased in the cerebrospinal fluid of most AD patients, and the levels of N-acetylglucosaminyltransferase III, a glycosyltransferase responsible for synthesizing a bisecting GlcNAc residue, were found to be highly expressed in the brains of AD patients as well (Wang et al., 2018). This evidence concerns the gene MGAT3 and Alzheimer disease.