MTM1 and centronuclear myopathy: Serotype 9 recombinant AAV vectors encoding MTMR2 were injected into the tibialis anterior muscle of Mtm1-deficient knockout mice, and a therapeutic effect was observed, suggesting strategies aiming at increasing MTMR2 expression levels in skeletal muscle may be beneficial in the treatment of myotubular myopathy (Danièle et al., 2018).