Inhibition of GRK2 increased oxygen consumption rates and ATP production,33 reduced the degree of myocardial remodeling,34 and abolished the AVP‐induced IL‐6 production and NF‐κB activation.35 Moreover, a very recent paper showed that GRK2 inhibition can be safely achieved with beneficial effects in diabetes, and beyond its effects on the glycemic profile, exerted the anti‐inflammatory and antioxidative effect on the heart, which indicated a potential therapeutic action on DCM.36 This evidence concerns the gene NFKB1 and familial dilated cardiomyopathy.