STING1 and neoplasm: Although multiple studies have found that injection of a STING agonist in a tumor-bearing mouse model enhanced the infiltration of T cells into the tumor microenvironment [37, 90], and several types of cells, such as DCs, macrophages and endothelial cells, have been identified to help infiltration of T cells into tumor microenvironment in responding to activation of STING pathway by exogenous STING agonists in different models, the direct effect of STING activation within T cells on their trafficking and infiltration is not evaluated currently.