SLC28A3 and viral infectious disease: In contrast, Africans and East Asians were among the populations with the highest frequency of rs56350726, a variant in SLC28A3 implicated in improved outcomes and reduced toxicity of antiviral hepatitis C virus (HCV) therapy (Doehring et al. 2011; Rau et al. 2013), suggesting potentially important implications for toxicity risk of nucleoside analogs used in the treatment of viral infections and various cancers.