GOLPH3 and hepatocellular carcinoma: GOLPH3 is a well-known oncogene in several solid tumors, such as hepatocellular carcinoma,17 ovarian cancer18 and CRC.19 Increasing number of studies revealed the fact that miRNAs result in target mRNA degradation or translational inhibition.20 To date, a series of tumor-suppressor miRNAs have been confirmed to target GOLPH3.