CCM2 and cervical cancer: To confirm this finding, all identified CCM2 isoform pairs were used to screen in HeLa cells (Immortalized Cervical cancer cells) and three primary human endothelial cell lines, Human Umbilical Vein Endothelial Cells (HUVEC), Human Microvascular Endothelial Cells (HMVEC), and Immortalized Human Cerebral Microvascular Endothelial Cells (hCMEC/D3) (Suppl. Fig. 2A–D), and final results were summarized in Table 3.