IL1β inhibition reduced tumour formation from 10/24 hind limb tumours in control mice to 3/22 hind limb tumours in Anakinra treated mice (42% vs 14%, p = 0.021, chi squared test) (Representative images of excised hind limbs in Supplementary Fig. 5G, representative H&E images in Fig. 5f). The gene discussed is IL1B; the disease is neoplasm.