The PKM1 isoform is expressed in the normal cells [4] and is associated with normal glucose metabolism wherein PKM2 isoform is overexpressed in cancer cells [5] and is associated with increased aerobic glycolysis, termed as Warburg effect, which is associated with the increased cell proliferation and reduced apoptosis [6], thereby PKM2 may be a potential therapeutic target for cancer treatment [7]. This evidence concerns the gene PKM and cancer.