Similarly, the risk of recurrence (ROR) scores, which are generated from PAM50 subtype data alone (RORS) or together with proliferation signature index (RORP) or tumor size (RORT), was also not significantly different between GR methylation groups (Table 5), suggesting that GR methylation is not associated with the PAM50 signature. The gene discussed is NR3C1; the disease is neoplasm.