Many lncRNAs were previously proven to be involved in the development and progression of HCC, including Highly Upregulated in Liver Cancer (HULC), H19, maternally expressed gene 3 (MEG3), lncRNA‐LET, HOTAIR, and MALAT1.27 For instance, HULC was confirmed to inhibit the activity of a series of microRNAs including microRNA‐372. The gene discussed is HOTAIR; the disease is hepatocellular carcinoma.