However KPD has been used in otherstudies of residents and emigrants from LMIC to denote newly diagnosed diabetes,usually after the age of 30 years of age, with symptoms and signs of diabetes,unprovoked ketosis (absence of provoking factor for ketosis such as infection),transient insulin requirement and absence of islet cells (ICAs Ab) and glutamicacid decarboxylase anti-bodies (GADAb) [12,29,32,34,35]. This evidence concerns the gene INS and infection.