CXCL8 and cancer: Cytokines and chemokines are important components of TME.1 Interleukin-8 (IL-8) or CXCL8 (C-X-C motif ligand 8) is a member of the chemokine family and associates with angiogenesis and endothelial cell migration.2,3 IL-8 participates in various cellular processes in cancer causing increased tumour progression and angiogenesis.