We recently reported that overexpression of Hnrnpf in RPTCs suppresses Agt expression, and attenuates systemic hypertension and renal injury in male Akita (type 1 diabetic murine model) Hnrnpf-Tg mice13 and db/db (type 2 diabetic murine model) Hnrnpf-Tg mice14. This evidence concerns the gene AGT and Hypertension.