We have reported previously that Hnrnpf overexpression in RPTCs attenuates hypertension and kidney injury in both diabetic Akita13 and db/db14 mice via inhibition of intrarenal Agt expression, implying an important role for Hnrnpf in modulating the development of hypertension and nephropathy in diabetic mice. This evidence concerns the gene HNRNPF and Hypertension.