BRAF and cancer: Of the cell lines characterized by the Cancer Cell Line Encyclopedia (CCLE) that possess a BRAF-V600E mutation (n = 94), and the Reverse Phase Protein Array (RPPA) data available from the MD Anderson Cell Line Project (MCLP, n = 650), 26 overlapped and had data pertaining to vemurafenib sensitivity in the Cancer Therapeutic Response Portal (CTRP) (Fig. 1 a, Additional file 1: Table S1).