Next, a database reporting the expression level of different genes in 68 meningioma cases was interrogated with BioGPS (see Material and Methods for details) to explore the relationship between PRKACA gene, coding for PKA CAT, and PKA regulatory subunits (PRKAR1A, PRKAR1B, PRKAR2A, and PRKAR2B) gene products. The gene discussed is PRKAR1B; the disease is meningioma.