SOX10 and colorectal cancer: Given that overexpression of NEDD9 implies poor prognosis in colorectal cancer patients [43], we confirmed a dramatic effect of MLT (0.5, 1 mM) and/or Ptero (20, 40 μM) on NEDD and SOX10/9, especially in SW480 and HT29 CRCs better than in HCT116 cells.