Also, among several target molecules, neural precursor cell expressed developmentally downregulated 9 (NEDD9), so called Cas-L (Crk-associated substrate L) or human enhancer of filamentation1 (HEF1), promotes proliferation [39] and metastasis [19,39] in breast cancer, colorectal cancer, and head and neck cancer [40,41]. The gene discussed is NEDD9; the disease is head and neck cancer.