S100A1 and melanoma: In total, 16 melanoma marker genes (S100A1, ABCB5, CDH19, MIA, SLC26A2, MCAM, S100A2, S100P, MAGEA4, TFAP2C, SFRP1, SERPINA3, CSPG4, TYRP1, IL13RA2, S100A7A) were highly expressed in melanomas with activating mutations (Figure 1A,C).