Abdulwahab et al. (2019) collected sera from healthy people and T2D patients for proteomic mass spectrometry and found that 62 proteins were differentially expressed in T2D, which were functionally grouped into 16 proteins, including heparin cofactor 2, Ig α-1 chain C region, and zinc-α-2-glycoprotein, the largest of which was an immune-related protein [33]. The gene discussed is SERPIND1; the disease is type 2 diabetes mellitus.